| Dai Xiaochang | 19-Jul-22 | 21-Oct-24 | ED | | Dr. Dai wishes to devote more time to his other commitments. |
| 21-Oct-24 | MbCC | | Dr. Dai wishes to devote more time to his other commitments. |
| 17-May-24 | CSO | | Due to his personal reasons |
| 25-Jan-21 | 19-Jul-22 | NED | | Dai has been re-designated from a non-executive Director to an executive Director |
| Dr. Francois Lebel | | 31-May-24 | CMedO | | To devote more time to his other commitments |
| Dr. Yang Lu | | 05-Nov-24 | CEO | | Re-designation as Chief Scientific Officer and from an executive Director to a non-executive Director. Dr. Lu will provide support to Dr. Poon and facilitate a smooth transition. |
| Dr. Yang Lu (Alias Patrick Lu) | | 23-Apr-25 | Hon Adv | | The Cessation allows the new management team room to focus its efforts on stringent internal control measures and on regulatory compliance. |
| 05-Feb-25 | NED, MbNC, AuRep | | Dr. Lu wishes to devote more time to his other commitments. |
| Evans David Mark | 12-Jul-21 | 20-Jun-24 | ED | | AGM ordinary resolutions regarding, re-election was not passed. Dr. Evans will remain as the Head of Drug Discovery and Collaboration of the Group |
| Ghias Mike M | 25-Jan-21 | 12-Jul-21 | NED | | |
| Hua Feng Mao | 20-Dec-21 | 20-Jun-24 | INED | | |
| Hua Fengmao | 20-Dec-21 | 20-Jun-24 | INED | | AGM ordinary resolutions regarding, re-election was not passed. |
| Huang Mincong | 25-Jan-21 | 01-Jan-25 | NED | | Mr. Huang wishes to devote more time to his other commitments. |
| 01-Jan-25 | MbAC | | Mr. Huang wishes to devote more time to his other commitments. |
| Lai Jiajun | 25-Jan-21 | 31-Aug-22 | NED | | Mr. Lai wishes to devote more time to his other commitments. |
| Law Shing Yvonne Mo Han | 20-Dec-21 | 01-Jan-25 | INED | | |
| Leung Leo Ting Cheung | | 30-Nov-24 | CoSec | | |
| Li Yunchun | 25-Jan-21 | 12-Jul-21 | NED | | |
| Liu Da | 25-Jan-21 | 30-Sep-22 | NED | | Mr. Liu wishes to devote more time to his other commitments |
| Lo Yee Hang | 01-Sep-25 | | INED, ChNC, Ch InvestigationC, MbAC | | |
| Lu Patrick Yang | 20-Dec-24 | 05-Feb-25 | Fdr, NED | | |
| 05-Nov-24 | 20-Dec-24 | Ch, Fdr, NED | | Dr. Lu will focus his efforts on business strategies in the US for the Group and has requested to retire from his positions. |
| 20-Dec-24 | CSciO | | Dr. Lu will focus his efforts on business strategies in the US for the Group and has requested to retire from his positions. |
| 15-Oct-20 | 05-Nov-24 | Ch, CEO, Fdr, Pres | | |
| Lu Yang | 05-Nov-24 | 05-Feb-25 | Non-executive Director | | |
| 15-Oct-20 | 05-Nov-24 | ED | | Re-designation as Chief Scientific Officer and from an executive Director to a non-executive Director. Dr. Lu will provide support to Dr. Poon and facilitate a smooth transition. |
| Molyneaux Michael V | 25-Jan-21 | 30-Nov-23 | ED | | Dr. Molyneaux wishes to devote more time to his other commitments |
| 30-Nov-23 | CMedO | | Dr. Molyneaux wishes to devote more time to his other commitments |
| Mr. Fengmao Hua | | 20-Jun-24 | MbAC, ChNC | | AGM ordinary resolutions regarding, re-election was not passed. |
| Mr. Leung Ting Cheung | | 30-Nov-24 | CoSec, AuRep, Proc Agt | | Resigned. Mr. Leung confirmed that he had no disagreement with the Board and there were no other matters relating to his resignation that need to be brought to the attention of the shareholders of the Company or The Stock Exchange of Hong Kong Limited. |
| Ms. Shing Mo Han, Yvonne | | 01-Jan-25 | INED, ChAC, MbNC | | Ms. Shing wishes to devote more time to her other commitments. |
| Ouyang Yunlong | 03-Jul-25 | 05-Jun-26 | NED | | Mr. Ouyang wishes to devote more time to his other commitments. |
| 01-Sep-25 | 05-Jun-26 | MbAC, MbCC | | Mr. Ouyang wishes to devote more time to his other commitments. |
| Poon Hung Fai | 01-Sep-25 | | Ch, AuRep | | |
| 05-Nov-24 | | CEO | | |
| 15-Oct-24 | 05-Nov-24 | ED | | |
| Ung Mo Nin | 20-Dec-21 | 01-Dec-25 | INED | | |
| Ung Monin | 20-Dec-24 | | Ch | | |
| 20-Dec-24 | 01-Dec-25 | INED | | Ms. Ung wishes to devote more time to decentralized life science and to expanding her law offices in China. Ms. Ung will remain as an advisor to the Company after her resignation. |
| 01-Dec-25 | Ch, ChCC, Ch InvestigationC, MbAC, MbNC, AuRep | | Ms. Ung wishes to devote more time to decentralized life science and to expanding her law offices in China. Ms. Ung will remain as an advisor to the Company after her resignation. |
| 20-Dec-21 | 20-Dec-24 | INED | | |
| Wang Edward Yongxiang | 10-May-24 | 20-Jun-24 | ED | | AGM ordinary resolutions regarding, re-election was not passed. Dr. Wang will remain as the Chief Production Officer of the Group. |
| Wong Eugene Yu Shan | 01-Sep-25 | | MbCC, Mb InvestigationC | | |
| 17-Feb-25 | | INED | | |
| Yin Huijun | 05-Jun-26 | | MbAC, MbCC | | |
| 01-Sep-25 | | NED | | |
| Yip Nigel Wing Kei | 15-Nov-22 | 31-May-24 | CFO | | To devote more time to his other commitments |
| Yu Albert Cheung Hoi | 20-Dec-21 | 18-Oct-25 | INED | | Dr. Yu wishes to devote more time to his other commitments. |
| 18-Oct-25 | ChNC, MbAC, MbCC, Mb InvestigationC | | Dr. Yu wishes to devote more time to his other commitments. |
| Yuen Yun Ting | 30-Nov-24 | | CoSec | | |
| Yun Zhang, Monica | | 31-Aug-23 | J-CoSec | | No reasons provided. |
| Zhang Jiankang | 12-Jul-21 | 21-Jun-25 | NED | | Mr. Zhang wishes to devote more time to his family and other commitments. |
| 21-Jun-25 | MbCC | | Mr. Zhang wishes to devote more time to his family and other commitments. |
| Zhang Monica Yun | | 31-Aug-23 | CoSec | | |
| Zhang Peng | 01-Sep-25 | | ChCC, MbNC, Mb InvestigationC | | |
| 03-Jul-25 | | INED | | |
