| Dr. Donald Kwok Tung Li | | 03-Jan-25 | INED | | Due to his other professional business commitments which require more of his time and devotion. |
| Dr. Yiyou Chen | | 20-Jun-22 | Ch | | Due to Company’s transition from clinical stage to commercial stage biotech with the successful launches and commercialization of both ColoClear and UU Tube |
| Kong Jiangnan | | 08-Aug-25 | INED | | To devote more time to her other commissions and support an orderly transition of the Company. |
| Mok Ming Wai | | 09-Sep-24 | J-CoSec, AuRep, Proc Agt | | No reasons provided |
| Mr. Lau Ngai Kee Ricky | | 14-Apr-25 | INED | | His belief that there is no longer room for him to fully fulfill his role effectively as an independent non-executive Director and the chairman of the Independent Special Committee, and to properly safeguard the interests of the Company and its minority shareholders; and his desire to devote more time to other engagements. |
| Mr. Yeqing Zhu | | 30-Dec-24 | CEO, ED | | Resigned from the positions of Chairman and Chief Executive Officer due to personal health reasons. Proposed removal from the position of Executive Director due to differing management style and philosophy from other Board members. Removed from any other positions within the Group with immediate effect. |
| Ms. Ng Weng Sin | | 14-Apr-25 | INED | | Her belief that there is no longer room for her to fully fulfill her role effectively as an independent non-executive Director and a member of the Independent Special Committee, and to properly safeguard the interests of the Company and its minority shareholders; and her desire to devote more time to other engagements. |
| Nisa Bernice Wing-Yu Leung | | 28-Feb-22 | NED | | Due to her other business commitments |
| Prof. Hong Wu | | 01-Oct-24 | INED | | Personal health reason |
| Yu Gao | | 09-Sep-24 | CFO | | No reasons provided |
